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Get Your Follow-up Colonoscopy After an Abnormal Stool Test

July 1, 2024 by Emily Grant

How often have you stopped short of the finish line on your health goals? A new study published in JAMA Network Open found that 52 percent of patients did not follow through with colon cancer screening recommendations when hidden blood was found in their stool samples.

Two Types of Colorectal Cancer Screenings

Cancer of the colon and rectum is a leading cause of cancer death in the United States. There are two types of screenings that help detect colon cancer or abnormalities:

  • Stool-based tests — These tests are less invasive and check for signs of cancer in a stool sample. You must repeat these tests more often than visual exams. Examples of these are fecal immunochemical tests (FIT) and stool DNA tests.
  • Visual exams — These cancer screening tests look for abnormalities in the structure of the rectum and colon. Colonoscopy, flexible sigmoidoscopy and virtual colonoscopy are the three tests available.

Colonoscopy is the gold standard for colon cancer screening. During colonoscopy, your doctor will visually inspect the entire colon and remove pre-cancerous polyps, which reduces the risk of cancer. If you do not have polyps, you may not need to repeat the test for 10 years.

Young patients and patients who are at average risk for colon cancer sometimes prefer stool-based tests (SBT) because they do not have to do colonoscopy prep or take time off work. If the test is positive, patients need to schedule a colonoscopy to determine whether the blood is from colon cancer or another source, like hemorrhoids or ulcers.

Less Than Half of Adults Complete Necessary Follow-Up Colonoscopy

Elizabeth L. Ciemins, PhD, MPH, from the American Medical Group Association in Alexandria, Virginia, led a quality improvement study to analyze whether screening-eligible adults chose to get a follow-up colonoscopy after an abnormal stool test.

“Based on our previous work, we recognized a serious deficit in patients receiving the necessary follow-up after an abnormal stool-based screening test for colorectal cancer,” said Dr. Ciemins. “Our accompanying qualitative research identified a lack of awareness in current rates of follow-up by primary care providers and others.”

The researchers looked at data from 38 health care organizations for 20,581 patients aged 50 to 75 years who received abnormal results from a colorectal cancer SBT. The team found that 47.9 percent had a follow-up colonoscopy within six months.

The study found that follow-up colonoscopy screening rates were lower among Black patients (37.1 percent) and patients with Medicare and Medicaid (49.2 and 39.2 percent, respectively).

“Use of SBTs may increase overall screening rates, but abnormal results must be followed up with a colonoscopy to diagnose CRC — ideally as soon as possible, but definitely within the six months after an abnormal test result,” the research authors wrote.

Tips Make Colonoscopy More Manageable

Have you received a positive stool-based test and you need to schedule a follow-up colonoscopy?

A colonoscopy might seem scary or intimidating, but the new prep solutions are low-volume, more palatable and easier to consume. Here are seven tips to make a colonoscopy prep more comfortable:

  1. Reduce or eliminate meat from your diet a few days before your prep day.
  2. You will need to spend one day on a clear liquid diet. Create variety in your clear liquids by purchasing assorted flavors of broth, gelatin and Italian ice. Just remember to avoid anything that has red or blue dye, as it may make it more difficult to examine the colon.
  3. Chill your colonoscopy prep liquid. Drink it chilled and chase it with cold water.
  4. Use a straw to drink the prep liquid. You can drink it faster and you will not taste it as much.
  5. Purchase soft toilet paper and flushable wipes.
  6. Plan to watch that new series or movie on prep day, as it will give you something to look forward to instead of dread!
  7. Plan an at-home project or activity that will occupy you on prep day.

Screenings Essential for Preventive Care

Preventive medical care is important for optimum health, but we often put health screenings at the bottom of our to-do list. Colon cancer is the second-leading cause of cancer death in the United States, but one-third of Americans are overdue for a colon cancer screening.

The American Cancer Society recommends that all adults who are at average risk for colon cancer begin screening at age 45. If you have a family or personal history of colon cancer, colon polyps, inflammatory bowel disease or hereditary colon cancer syndromes such as Lynch syndrome or FAAP, you should undergo screening at an earlier age.

Most insurance plans provide coverage for screening colonoscopy beginning at 45, but call your insurance provider for more details about your health plan. Now that we are in the second half of the year, it is important to schedule procedures as soon as possible.

Are You Looking for a GI Specialist?

Perhaps you have not scheduled a colonoscopy or GI consultation because you need to find a gastroenterologist. Our fellowship-trained gastroenterologists are accepting new patients at our GI facilities nationwide. Call our centers today to ask about colon cancer screening or any other digestive procedure. We offer treatment for GERD, diverticulitis, Crohn’s disease, ulcerative colitis and other chronic digestive system conditions.

Filed Under: Colon Cancer, Colonoscopy, Prevention

Colon Cancer Prevention? Regular Screenings Are Key.

June 3, 2024 by Emily Grant

Colorectal cancer is preventable with regular screenings, and it is easier to treat if doctors diagnose it at an early stage before the disease spreads.

Colon Cancer Is a Common but Generally Preventable Cancer

Did you know nearly 60 million people between 45 and 85 are eligible for colon cancer screening in the United States? According to a study published in JAMA Network Open, the screening-eligible population is 57.1 to 59.6 million people.

Colon cancer is the second-leading cause of cancer death among adults, but it can affect individuals of all ages. The American Cancer Society recommends that everyone who is at average risk for colon cancer begin regular screening at age 45.

What Are the Screening Options for Colon Cancer?

There are two main categories of colon cancer screening methods: tests that analyze stool samples and visual examinations. All tests have different risks and benefits.

  • Stool-based tests — These tests are non-invasive and check for signs of cancer in a stool sample. You must repeat these tests more often. Examples of stool-based tests include the following:
    • Fecal immunochemical test (FIT) — You must repeat this test every year.
    • FIT/Stool DNA test — You must repeat this test every three years.
    • Guaiac-based fecal occult blood test (gFOBT) — You must repeat this test every year.
  • Visual exams — These cancer screening tests look for abnormalities in the structure of the rectum and colon. Examples of visual exams include the following:
    • Colonoscopy — This is the gold standard for colon cancer screening because a doctor can remove polyps during the procedure and reduce the risk of cancer. If you do not have polyps, you may not need to repeat the test for 10 years.
    • CT colonography — Must be repeated every five years.
    • Sigmoidoscopy — Must be repeated every five years.

Even though colonoscopy is the most comprehensive colon cancer screening of the colon and rectum, stool-based tests have the benefit of being non-invasive and convenient. It is important to remember that if you get an abnormal result from a stool-based test, you must follow up with a colonoscopy (American Cancer Society). Follow-ups are recommended within six months following the abnormal test.

Deficits in Colon Cancer Screenings

Unfortunately, many Americans are not up to date on colorectal cancer screening. Reasons can range from avoidance to lack of education, but millions of people are not getting screened at recommended intervals or not getting tested at all.

“We hope our estimates can support policy makers and health care stakeholders to advance initiatives surrounding colorectal cancer screening to prevent this disease or identify it earlier when more can be done to treat it,” said Derek W. Ebner, MD, of the division of gastroenterology and hepatology at the Mayo Clinic.

Dr. Ebner conducted a study among people between the ages of 45 and 85 who were at average risk for colon cancer. In that sample, 59.3 percent to 61.8 percent were current on screening. The final estimated population that was eligible for screening was 57.1 to 59.6 million people, including individuals who were eligible for screening the following year.

Who Is at High Risk for Colorectal Cancer?

People qualify as increased or high risk if they have any of the following:

  • A family history of colorectal cancer
  • A personal history of colorectal cancer or specific type of polyp
  • A personal history of inflammatory bowel disease (like ulcerative colitis or Crohn’s disease)
  • A confirmed or suspected hereditary colon cancer syndrome, like familial adenomatous polyposis (FAP) or Lynch Syndrome (hereditary non-polyposis colon cancer)
  • A history of radiation in the abdomen or pelvis because of prior cancer (ACS)

You May Be Due for a Colon Cancer Screening

If you are 45 or older, talk to your doctor about whether you are eligible for colon cancer screening this year. Most insurance plans provide coverage for screening colonoscopy for patients beginning at age 45, so call your insurance plan to verify coverage.

Locate a Colorectal Screening Center Near You

Our GI centers have fellowship-trained gastroenterologists to meet all your digestive system needs. Whether you seek a colon cancer screening or a consultation for a chronic GI problem, our physicians and caring staff are available to serve you. Call today to make an appointment.

Filed Under: Colon Cancer, Colonoscopy, Prevention

Genetic Link Between Colon Cancer Risk and Meat Consumption?

May 1, 2024 by Emily Grant

It’s finally barbecue season again. The aroma of grilled hot dogs and hamburgers is the smell of summer and brings back memories of family picnics and ball games.

Although burgers and dogs are tasty, you may consider eating other proteins for your overall health. Past research shows eating red and processed meat can increase your risk for colorectal cancer (CRC). A new study suggests genetics can alter colon cancer risk based on red or processed meat consumption.

New Study Underscores Health Risks of Red and Processed Meat

A new study supported by the National Institutes of Health and led by the USC Norris Comprehensive Cancer Center, part of the Keck School of Medicine of USC, found that people who ate red or processed meat were, respectively, 30 or 40 percent more likely to develop colon cancer.

The researchers studied data on more than 29,000 people with colon cancer and more than 39,000 without colon cancer. During the study, they isolated two genes, HAS2 and SMAD7, that affected colon cancer risk based on red or processed meat consumption.

“These findings suggest that there’s a subset of the population that faces an even higher risk of colorectal cancer if they eat red or processed meat,” lead author Mariana C. Stern, PhD, a Professor of Population and Public Health Sciences and Urology, told Medical Xpress.

“It also allows us to get a peek at the potential mechanism behind that risk, which we can then follow up with experimental studies,” added Dr. Stern, who is also the Ira Goodman Chair in Cancer Research and the associate director for Population Science at the USC Norris Comprehensive Cancer Center.

The study made significant progress in establishing the connection between red and processed meat and colon cancer, but the team has not found a causal link for the genetic variants.

“This gives us some important food for thought,” said Dr. Stern. “We do these gene-environment interaction studies when we know there’s a clear association between an environmental exposure and a disease, but what happens in between is still a black box.”

What Are Some Alternatives to Red or Processed Meat?

Healthier alternatives to hamburgers, steak, hot dogs, sausage and deli meat include lean poultry like chicken or turkey breast. Poultry provides an excellent source of flavorful protein without the cancer risk. Try eating fish like salmon or tuna, which are rich in omega-3 fatty acids. Adding some seasonal vegetables to the menu will help you be satisfied and satiated.

Also, consider an alternate cooking method for proteins than grilling. Heterocyclic amines (HCAs) and polycyclic aromatic hydrocarbons (PAHs) are chemicals formed when beef, pork, fish or poultry cooks at high temperatures. Laboratory studies show HCAs and PAHs change the DNA in meat and can increase the risk of cancer.

Routine Screenings Can Detect and Even Prevent Colon Cancer

It is estimated there will be about 106,590 new cases of colon cancer and 46,220 new cases of rectal cancer in 2024. Of all the cancer deaths in people younger than 50, colorectal cancer is the leading cause of death in men and the second-leading cause of death in women.

Routine screening is the most effective way to prevent CRC, even more so than diet or exercise. Because colon cancer can develop slowly without symptoms, it is important for adults at average risk to begin screening at age 45. If you have risk factors, like a family history of colon cancer or colon polyps, inflammatory bowel disease or hereditary colon cancer, you should start screening earlier.

Several options are available to screen for colorectal cancer. The goal of colonoscopy is to find and remove polyps growing on the colon wall. Most polyps are benign; however, if they are not removed, some could become cancerous. If the exam does not detect polyps and you are not at higher risk for colon cancer, your next screening may be in 10 years.

If you choose to take an alternate screening test and your result is positive, you will need a follow-up colonoscopy to determine the cause of the positive result.

Don’t Ignore Potential CRC Symptoms

Talk to your doctor if you experience any of these common symptoms for colon cancer: abdominal pain, blood in the stool, changes in bowel habits, unexplained weight loss or vomiting.

If you have digestive symptoms, you should consult your doctor, regardless of your age.

Find a Gastroenterologist Near You

When was the last time you had a colorectal cancer screening? Scheduling your colonoscopy at an ambulatory surgery center may be a good option because these centers are dedicated to specific procedures and may be less expensive.

Physicians at our colon cancer screening centers are accepting new patients and look forward to serving you. Call today to make an appointment with a fellowship-trained gastroenterologist.

Filed Under: Colon Cancer, Colonoscopy, Nutrition, Prevention

Study Finds Tumor Bacteria Differs in Young-Onset Colon Cancer

April 1, 2024 by Emily Grant

A new study suggests that young-onset colon cancer patients may have unique tumor-related bacteria compared to average-age colon cancer patients.

Young-onset colorectal cancer (CRC) refers to cancer of the colon or rectum in people younger than 50. More cases are occurring and often leading to death, with most not caused by inherited syndromes. Average-onset CRC is defined as older than 60.

Tissue Differences in Young-Onset Colon Cancer Tumors

The study explored factors that could contribute to the rise in young-onset colon cancer. The research analyzed colon tissue samples from 136 people diagnosed with CRC before age 50 and then compared them to samples from 140 older patients (above age 60) with CRC.

The research found young-onset colon cancer patients may have unique tumor-related bacteria that causes left-sided, rectal and advanced stage tumors.

Young-Onset Colon Cancer Incidence Increasing

Since 2011, colorectal cancer incidence has been increasing by two percent a year in adults younger than 50 as well as adults between 50 and 54.

“The unexplained rise of young-onset colorectal cancer is of great concern,” said Alok Khorana, MD, oncologist and primary investigator of the study. “Our team discovered that bacteria were more abundant and compositionally distinct in tumors from young-onset patients. These insights help us to better understand the disease causes and inform new prevention approaches, diagnostic markers and therapeutic targets.”

Next Steps in Young-Onset Colon Cancer Research

The researchers found the bacteria in the tumor. They will now research how to use this information and create plans to tackle the issue.

“We will need to compare the bacteria to that of individuals who don’t have colorectal cancer,” said Shimoli V. Barot, MD, medical oncologist and first author of the paper. “Then we will try to figure out the role bacteria play in the pathogenesis of early-onset colorectal cancer. We want to determine what these bacteria are secreting, how they are interacting with the immune system around the tumor area and how the immune system could be primed to fight these bacteria.”

Through this research, Dr. Barot hopes they can discover new screening biomarkers and drugs that target tumor-related bacteria.

“Further research is needed into how lifestyle factors such as diet, medications and obesity may impact gut bacteria and contribute to young-onset colon cancers,” added Naseer Sangwan, PhD, a first author of the paper (Medical Xpress).

Begin Colon Cancer Screenings at Age 45 or Before

Most colorectal cancer forms from precancerous tissues, called polyps, that grow in the rectum or colon. Colon cancer is highly preventable with routine screenings. Because colon cancer can develop slowly without pain or symptoms, it is important to follow screening guidelines.

Adults at average risk for colon cancer should begin screening at age 45. If you have a family history of colon cancer or colon polyps, you should start screening earlier. Symptoms of colorectal cancer include changes in bowel movements, presence of blood in stool and abdominal discomfort. If you experience any of these symptoms, regardless of your age, make an appointment to see your doctor.

Colonoscopy Is the Gold Standard for Colon Cancer Screening

Several colon cancer screening methods are available, but colonoscopy is the most effective. This procedure allows your gastroenterologist to examine the entire colon and remove polyps before they become cancerous. A colonoscopy typically lasts less than an hour. If your doctor does not detect abnormalities and you are not at higher risk for colon cancer, screening is typically done every 10 years.

Find a Gastroenterologist Near You

Are you under the care of a fellowship-trained gastroenterologist? If not, we can help you find a doctor who specializes in digestive health. Our colon cancer screening centers are located throughout the country, and our physicians are accepting new patients. Call today to make an appointment for a screening colonoscopy.

Filed Under: Colon Cancer, Colonoscopy, Nutrition, Prevention

No Excuses: Colon Cancer Survivor Encourages Colonoscopy

March 1, 2024 by Emily Grant

Colon cancer survivor Karen Fisher transformed her pain of diagnosis into a purpose to help others.

The Inverness, Florida, pharmacist helps newly diagnosed colorectal cancer (CRC) patients find support resources and encourages adults to get timely preventive screenings.

“I have been able to help friends, coworkers and neighbors get screened for colon cancer,” Fisher said. “It makes me feel good to be able to help other people prevent going through what I went through.”

Fisher learned she had Stage 2A colon cancer at age 54.

“Colon cancer wasn’t really even on the radar,” she said. “So, it was kind of a shock.”

March is National Colorectal Cancer Awareness Month. This monthlong campaign promotes the research, prevention, diagnosis, treatment and, ultimately, cure for this disease.

The American Cancer Society (ACS) estimates about 106,590 people will be diagnosed with colon cancer and about 46,220 with rectal cancer in 2024.

Don’t Make Excuses for Not Getting Screened

In 2016, experts recommended that colorectal cancer screenings begin at 50 for people at average risk for the disease. Fisher turned 50 that year but made excuses to postpone her screening.

“I was busy with work and teenagers and after-school activities, and you know, moms take care of everybody else but themselves,” she said. “I had even driven my husband to his colonoscopy when he turned 50. He’s five months younger than me.”

The U.S. Preventive Services Task Force recommended the screening age be lowered to 45 in 2021 because of an increase in cancer in younger people. CRC is now the number one cause of cancer death in men and the second in women younger than 50.

Fisher had no family history of CRC and did not think she had any symptoms.

“I had blood in the stool, but at the time I was perimenopausal, and I thought I was spotting between periods,” she said. “Looking back, I can recognize that yes, I had a symptom.”

Fisher’s health insurance required her to get a colonoscopy at the hospital where she works.

“That was one thing that prevented me from getting screened in a timely manner. I didn’t want to get naked in front of my coworkers,” she said. “I knew everyone in the endoscopy department. I didn’t want them to see me, so I put it off.”

Colonoscopy Reveals Cancer Diagnosis

In May 2020, Fisher tried to donate blood but was turned away because her hemoglobin level was low. Blood tests revealed Fisher had iron deficiency anemia. To determine the cause, her family doctor ordered a colonoscopy.

Because of the COVID-19 pandemic, a backlog of cases at the hospital, and the urgent nature of her anemia, she was able to get a medical exception to have the procedure at Citrus Endoscopy and Surgery Center in nearby Crystal River.

Gastroenterologist Trupti Shinde, MD, performed the colonoscopy and found a 5 cm mass in Fisher’s colon. Dr. Shinde referred her to Parth Patel, MD, general surgeon, to remove the tumor and scheduled surgery in July 2020. Pathology revealed that the cancer was Stage 2A.

“It was just such a whirlwind of activity with me. You know, me still trying to work full time, too, and trying to process all of this in my head,” Fisher said.

A Foundation to Help CRC Patients

About six months post-surgery, Fisher scheduled a follow-up appointment with Dr. Shinde. The two discussed the lack of support and resources for colorectal cancer patients and caregivers.

“After recovery, I asked all my doctors about a support group for colon cancer but none of them knew of any,” Fisher said. “I did a lot of research online and found a lot of good resources. I wanted to share them with other colon cancer patients.”

Patient and doctor began offering support groups at the local library without much success. Undeterred, they refocused their efforts on compiling a list of patient resources into a pamphlet designed by Fisher’s son. Then they shared the pamphlets with local surgery centers and healthcare facilities for distribution to CRC patients.

From this outreach, Fisher worked with Dr. Shinde and Dr. Patel to create the nonprofit Citrus Colorectal Cancer Foundation. The foundation started in June 2021, Fisher’s one-year “cancerversary.”

The foundation offers direction for educational, financial and emotional support for CRC patients, caregivers and the community. The foundation is planning ColonFest ‘24 on March 23 and the second annual Charity Casino Night in April.

A New Survivor Lifestyle

Currently, there are more than one million colorectal cancer survivors in the U.S.

Fisher is fully healed three and a half years after her surgery.

“Everything is back to normal, and I can barely see the scars from the surgery,” she said.

A self-proclaimed chocoholic and a junk food junkie, Fisher adopted a healthier lifestyle, eating whole grains, fruits and vegetables and avoiding too much red meat, sugary foods and drinks.

“I lost 25 pounds after my surgery and recovery,” she said. “I feel like if I eat junk food then my cancer might come back.”

Even more so than diet or exercise, experts recognize regular colon cancer screening is the most effective way to prevent colorectal cancer. Fisher said she gets all her health screenings on time and doesn’t self-diagnose health conditions anymore.

Fisher, now 57, advises people not to make excuses and get screened on time.

“There are many types of colon cancer screening available these days, but I always recommend a colonoscopy,” Fisher said.

During a colonoscopy, your doctor can find and remove any polyps — often before they become cancerous. Colonoscopy is the only screening method that can detect and prevent colorectal cancer.

If you choose to take a stool test and receive a positive result, you need a follow-up colonoscopy to determine the cause.

Fisher keeps tabs on her family’s health screenings. One in three people with colorectal cancer have family members who also had it, according to the ACS. People with a family history of colorectal cancer, past polyps or specific genetic cancer syndromes should start screening earlier.

“My family is more aware of possible colon cancer symptoms since it can run in families,” she said. “They have been very supportive of me and my journey.”

In 2025, Fisher is looking forward to celebrating five years with no evidence of disease. She is even considering cheating on her diet.

“Maybe, once I reach the five-year mark, I will celebrate with some chocolate cake,” she said.

After retirement, Fisher said she wants to share the foundation’s mission in person across the U.S.

“I would love to buy an RV and travel all over the country, delivering my pamphlets to every scoping center I can find,” she said. “I would love to have regular support group meetings and help others go through this unwanted journey.”

Schedule Your Colonoscopy

CRC diagnosis in adults 40-49 has increased by nearly 15 percent in the past decade. Younger people tend to have more aggressive tumors that may be more difficult to treat.

Experts recommend colorectal cancer screenings begin at age 45 for adults who are at average risk.

“Prevention is a cure, and we have to prevent bad things,” Dr. Shinde said. “And I tell my patients, if you’re healthy and you want to do all these things in your life, then you are the perfect candidate to get the colonoscopy because it’s the best preventive tool.”

Scheduling your colonoscopy at an ambulatory surgery center (ASC) may be a good option because ASCs are dedicated to specific procedures and may be less expensive.

“A great colonoscopy is not a job of only a physician. It’s a team,” Dr. Shinde said. “It’s a team effort, and it’s a well-oiled machine at an ASC.”

Getting screened is critical to detecting and preventing colorectal cancer. If you are 45 or older and you need a doctor, we can help you find our GI centers located nationwide. Call today to make an appointment.


This article is designed for educational purposes only. The information provided should not be used for diagnosing or treating a health concern or disease. It is not a substitute for professional care. If you have or suspect you may have a health concern, you should consult your healthcare provider.

Filed Under: Colon Cancer, Colonoscopy, Prevention

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